CRC 779

Neurobiology of Motivated Behavior

Project Z01

Proteome Analysis and Mass Spectrometry

PD Dr. Thilo Kähne

PD Dr. Thilo Kähne

Prof. Dr. Michael Naumann

Prof. Dr. Michael Naumann

The working plan of TP Z01 combines the cooperative mass spectrometry-based work with other projects of the CRC and the work on molecular differentiation of appetitive- and aversive reinforced learning within the Integrative Paradigm. TP Z01 contributes to selected work packages of six projects within the CRC incurring a series of proteome analytical work to support the investigation of learning- and memory relevant cell biological mechanisms. A broad panel of established analytical methods is available and should be further developed with respect to selective requirements.

Workflow of quantitative analysis of changes in synaptic proteoms upon aversively motivated discrimination learning.

Workflow of quantitative analysis of changes in synaptic proteoms upon aversively motivated discrimination learning.